Chair
Dr. Anjana Bhardwaj
The University of Texas MD Anderson Cancer Center
Resource Sharing Working Group
Facilitating network-wide sharing of scientific resources, models, assays, data, and expertise to accelerate cancer immunoprevention research and reduce duplication across CIP-Net sites.
Mission
To promote collaborative, efficient, and reproducible cancer immunoprevention research by identifying shared needs, cataloging available resources, and facilitating access to expertise, data, SOPs, models, and institutional capabilities across the CIP-Net network.
Leadership
Co-Chair
Dr. Henry Withers
Roswell Park Comprehensive Cancer Center
Objectives
Cancer immunoprevention research often requires specialized animal models, humanized systems, HLA-restricted tools, custom reagents, standardized assays, and long development timelines. The Working Group helps CIP-Net sites operate as a coordinated network rather than isolated laboratories.
- Identify resource needs and shareable assets across CIP-Net investigator sites.
- Reduce duplicated effort by helping investigators locate existing models, SOPs, datasets, reagents, and expertise.
- Support standardized resource categories, submission templates, and a centralized resource registry.
- Coordinate DRCC-supported bioinformatics, statistical, and data infrastructure resources.
- Explore responsible sharing mechanisms for resources that may require MTA, IP, IRB, or other institutional review.
- Prepare resource-sharing updates and recommendations for CIP-Net leadership, NCI program staff, and the Annual Meeting.
Resource Categories
The Working Group organizes network resources into practical categories that can be searched, requested, and updated through the CIP-Net Intranet.
Bioinformatics
Pipelines, software, NGS analysis, statistics, and DRCC support pathways.
Mouse Models
Specialized, humanized, syngeneic, and disease-relevant prevention models.
Cell Lines
Engineered target cells, HLA-expressing lines, organoids, and tumor models.
Plasmids & Constructs
HLA constructs, vaccine templates, biological materials, and related reagents.
SOPs
Validated protocols for assays, flow cytometry, IHC, microbiome, and animal work.
Datasets
RNA-seq, scRNA-seq, spatial, microbiome, and other shareable datasets.
Core Facilities
Institutional cores, specialized equipment, NGS, imaging, and technical services.
Expertise
Technical consultation, troubleshooting, experimental design, and cross-site support.
Current Initiatives
Developing a centralized CIP-Net Intranet registry
for SOPs, mouse
models, plasmids,
cell lines, datasets, core facilities, and institutional expertise.
Prioritizing assay SOPs and validated protocols,
including immunology
assays,
flow cytometry, ELISpot, multiplex IHC, microbiome profiling, and animal
procedures.
Connecting sites that need resources with sites that
can offer animal
models,
technical expertise, RNA-seq datasets, NGS capabilities, or bioinformatics
support.
Coordinating DRCC-supported analysis, pipeline
standardization, data
infrastructure,
and future opportunities such as a cross-cancer single-cell sequencing
atlas.
Identifying unmet needs, including specialized
instrumentation, mass
spectrometry,
NMR, chemical synthesis, vaccine production, HLA models, plasmids, and
antibody panels.
Preparing progress summaries for the CIP-Net Annual
Meeting, including
survey findings,
resource gaps, collaborations, and future plans for network-wide sharing.
Contact the DRCC
For questions about the Resource Sharing Working Group, resource registry, SOP submissions, or DRCC support pathways, please contact the CIP-Net Data and Resource Coordinating Center.